Pharmaceutical Industry

..."I think the question is, should one drug compound do so much?" said Shannon Brownlee, author of Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer.

"This is a drug that may have a really serious side effect called suicide," Brownlee said. "Don't we have other drugs available that are safer and just as effective for such things as the management of chronic knee and low back pain?"... LINK

A few weeks ago, devoted listeners of National Public Radio were treated to an episode of the award-winning radio series The Infinite Mind called "Prozac Nation: Revisited." The segment featured four prestigious medical experts discussing the controversial link between antidepressants and suicide. In their considered opinions, all four said that worries about the drugs have been overblown.

The radio show, which was broadcast nationwide and paid for in part by the John D. and Catherine T. MacArthur… more

Do you want to Google your genes or peer into your future risks of heart disease or cancer? Now you can, according to direct to consumer testing companies. Gone are the days when genetic testing was limited to doctors ordering tests for rare, but prognostically potent, single gene disorders such as Huntington’s disease, Duchenne’s muscular dystrophy, or cystic fibrosis. Thanks to an explosion of newly discovered single nucleotide polymorphisms, or SNPs (pronounced snips), companies are marketing genetic tests for traits… more

Once upon a time there was an industry called pharma that was interested in doing well and doing good. Run by doctors and chemists, drug companies employed battalions of researchers whose scientific efforts resulted by mid-century in a flood of life-saving drugs, including antibiotics, vaccines, tranquilizers, antihistamines and steroids. As George Merck, president of the company founded by his father, put it in 1950, "We try never to forget that medicine is for the people. It is not for the… more

Felt a little short of breath the other day, walking up a hill. Uh-oh. A nugget of worry lodged for a moment in my mind. At 50-something, I'm in decent enough shape. I don't smoke. I walk several miles most days, and I can still beat my 40-something friend at tennis. Not exactly a candidate for a heart attack. But still. I've read all those stories about women like me, the ones with no risk factors for cardiac disease who… more

New generation antidepressants aren’t all they’re cracked up to be. That seems to be the central message in the meta-analysis published this week by Irving Kirsch and colleagues in PLoS Medicine,[1] and it was this message that made the headlines. Kirsch’s conclusion follows on the heels of similar studies showing that statins are useful in only a small subset of patients taking the drugs[2] and earlier studies finding that the safety and performance of cyclo-oxygenase-2 (COX 2) inhibitors were worse… more

If you’ve never suffered the agony of low back pain, don’t worry -- chances are you will. About two-thirds of adults are hit with low back pain at some time in their lives, and for many the pain is sufficiently unbearable to send them hobbling into the doctor’s office. Yet although back pain is one of the most common conditions around, and although it costs billions of dollars each year in lost productivity, doctors still disagree over everything from how… more

Is a CT scan always necessary after your child suffers a bump on the head? Should you think twice before undergoing surgery for lower back pain? Are your elderly parents going to be allowed to die at home, or will they spend their last few weeks in a hospital, hooked up to machines and tubes, subjected to painful, unnecessary procedures?

These are the kinds of questions you may find… more

Shannon Brownlee discusses direct-to-consumer drug marketing and the media...

BROOKE GLADSTONE: How do the drug companies make use of the press?

SHANNON BROWNLEE: Let me answer the question by kind of going at it from the perspective of the media, who are bombarded with information from a variety of sources.

One of those sources is The National Sleep Foundation, which sends out its poll and wants us to write about the results of that poll.

Number two,… more

...Some drug industry critics are not so surprised that advertising oversight has slackened. "The question is whether the industry has gotten better at complying with the rules or the FDA has gotten worse at enforcing them. It's probably a combination of the two," says Shannon Brownlee, author of the new book Overtreated: Why Too Much Medicine Is Making Us Sicker and Poorer...

The book describes how the industry fought the FDA to loosen ad restrictions on the basis of… more